What is Astragalus root?Functions,application and modern research about Astragalus root and its effective components?

Contents

• Botanical Description of Astragalus.
• Astragalus Root Spices and Preparation.
• Constituents and Phytochemicals of Astragalus Root.
• Narrative History of Astragalus.
• Modern Uses and Application of Astragalus root.
• Improve immune function:Astragalus as antiviral agent.
• Astragalus Cardiovascular effects.
• Research Update:Anti-aging effect of astragalosides.
• Astragalus Root combination and Suggestions.
• Astragalus Observational Studies Case Reports.
• Quantitative Analysis of Astragloside IV.
• Uses based on tradition or theory.
• Application,Administration and Dosing.
• Astragalus Membranaceus Research Update.
• Photo Gallery of Astragalus membranaceus.

Constituents and Phytochemicals of Astragalus Root.:

Phytochemicals of Astragalus Root:ASTRAGALOSIDE-I,Astragaloside-II,Astragaloside-III,Astragaloside-IV,Astragaloside-V,Astragaloside-VI,Astragaloside-VII,Astraisoflavan,Astraperocarpan,Betaine,Calycosin,Formononetin,Gaba,Isoastragaloside-I,Isoastragaloside-II,Isoastragaloside-IV,Isoliquiritigenin,Ononin,Soyasaponin-I.
   Active ingredients:total Astragloside, triterpene glycosides, polysaccharides. Astragalus contains numerous components, including flavonoids, polysaccharides, triterpene glycosides (e.g., astragalosides I-VII), amino acids, and trace minerals. Astragalus appears to restore T-cell (a specific type of white blood cell ) counts to relatively normal ranges in some cancer patients.
 Astragalus contains several characteristic triterpenoid saponins known as Astragalosides which can be used for the identification and standardization of the plant . The principle compound, astragaloside IV is typically found at 0.15 mg/g. In addition it contains at least 6 isoflavonoids (total 0.02% w/w) including the estrogenic flavonoid fromononetin. Cell wall derived polysaccharides have been isolated from A. membranaceus var mongholicus and designated as astragalans I-III.
 Key Components:asparagine,calcyosin,formononetin,astragalosides,kumatakenin,sterols.
 Several chemical constituents of astragalus have been identified as potential active compounds, including saponins, flavonoids, polysaccharides and glycosides. Astragalus is often combined with other adaptogenic herbs, such as ginseng, and promoted as a guard against various internal and external stressors. Combination of astragalus with echinacea is common for protection against common infections of the mucous membranes (cold and flu).
 Other Content:soyasapogenoside; formononentin; calycosin; canavanine;gama-aminobutyric acid; asparamide; prolin;trace minerals such as iron,zinc,etc;dimethyl 4,4-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2-dicar-oxylate; daucosterol; kaempferol; quercetin; quercetin-3-glucoside; isorhamnetin; formononetin4-O-glucoside; aspartic acid; threonine; serine; glutamic acid;glycine; alanine; methionine; isoleucine; leucinine; trytophan; phenylalanine; cystine; Beta-sitosterol; linoleic acid; linolenic acid; astrafalussaponin I,II,III; astragaloside V-VIII; kumatakenin; 1-3-hydroxy-9-methoxpterocarpan; choline; betaine; follic acid; astragaloside I,astragaloside II, astragaloside IV; 3S-(-)mucronulatol-7-D-glucopyranoside; astraglan I, astraglan II, astraglan III; etc.
 New identified:some new chemicals got identified from astragalus root,such as astraisoflavanin (3S-(-)-mucronulatol-7-O-D-glucopyranoside) from alcoholic extract21..
 Scientific Support:Most of the scientific data on astragalus comes from Chinese clinical evidence, where astragalus appears to stimulate the immune system in patients with infections. At least one clinical trial in the U.S. has shown astragalus to boost T-cell levels close to normal in some cancer patients, suggesting the possibility of a synergistic effect of astragalus with chemotherapy. In animal studies, astragalus extracts have been shown effective in preventing infection of mice by influenza virus, possibly by increasing the phagocytotic activity of the white blood cells of the immune system.Agroastragaloside II, a new astragaloside was isolated from the hairy root culture of Astragalus membranaceus,its structure got identified(55.).
 Some recent analytic study identified that hairy roots of Astragalus membranaceus contains good source of crude saponin and astragaloside i.v,polysaccharide and isoflavonoid compounds,suggest hairy roots may be a new source of A. membranaceus(69.). Some test identified Eight flavonoids from astragalus root recently,they are calycosin-7-O-beta-D-glucoside, calycosin-7-O-beta-D-glucoside-6"-O-malonate (2), ononin, (6aR,11aR)-3-hydroxy-9,10-dimethoxypterocarpan-3-O-bet a-D-glucoside, calycosin, (3R)-7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-beta-D-glucoside, formononetin-7-O-beta-D-glucoside-6"-O-malonate and formononetin by direct comparison with the isolated standards from Astragalus Root(73.).
 Studies on pharmacological junctions proved that similar to the natural A. membranaceus, hairy root of Astragalus membranaceus has senility-preventing, antioxidizing and immunomodulating functions(82.).

Reference:

• 1.What is Astragalus root?Functions,application and modern research about Astragalus root and its effective components?

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:09th,Oct.2010.