What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?

Contents

• Standard Description of Common cnidium fruit extract.
• Basic Botanical Data of Cnidium plant and Cnidium Seeds.
• Pharmacology Actions of of Osthol.
• Cnidium Monnier works for Eva and Adam.
• Application and Indications of Osthole.
• HPLC Determination of Osthole in Rat Plasma after Oral Administration of Fructus Cnidii Extract.
• Why must throw away Viagra and other out dated thing and choose Natural Cnidium Fruit?
• Safety and Acute toxicity
• Cnidium Monnier Research Update.
• Photo Gallery of Cnidium monnieri.

HPLC Determination of Osthole in Rat Plasma after Oral Administration of Fructus Cnidii Extract.:

A simple and sensitive high-performance liquid chromatographic (HPLC) method is developed for the determination of osthole in rat plasma and applied to a pharmacokinetic study in rats after administration of Fructus Cnidii extract. After addition of fluocinonide as an internal standard, plasma samples are extracted with diethyl ether. HPLC analysis of the extracts is performed on a Hypersil ODS2 analytical column, using methanol-0.4% acetic acid (65:35, v/v) as the mobile phase. The UV detector is set at 322 nm. The standard curve is linear over the range 0.0520~5.20 ug/mL (r = 0.9979). The mean extraction recoveries of osthole at three concentrations were 81.0%, 91.2%, and 90.7%, respectively. The intra- and interday precisions have relative standard deviations from 1.9% to 4.9%. The limit of quantitation is 0.0520 ug/mL. The HPLC method developed can easily be applied to the determination and pharmacokinetic study of osthole in rat plasma after the animals are given the Fructus Cnidii extract. The plasma concentration of osthole from six rats showed a Cmax of 0.776 +- 0.069 ug/mL at Tmax of 1.0 +- 0.3 h.

Reference:

• 1.What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:08th,Oct.2010.