What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?

Contents

• Standard Description of Common cnidium fruit extract.
• Basic Botanical Data of Cnidium plant and Cnidium Seeds.
• Pharmacology Actions of of Osthol.
• Cnidium Monnier works for Eva and Adam.
• Application and Indications of Osthole.
• HPLC Determination of Osthole in Rat Plasma after Oral Administration of Fructus Cnidii Extract.
• Why must throw away Viagra and other out dated thing and choose Natural Cnidium Fruit?
• Safety and Acute toxicity
• Cnidium Monnier Research Update.
• Photo Gallery of Cnidium monnieri.

Safety and Acute toxicity:

Osthol:

 Chemical Name: Coumarin,7-methoxy-8-(3-methyl-2-butenyl)-
 CAS: 484-12-8.Molecular Formula: C15-H16-O3.Weight: 244.31
 Synonyms: 2H-1-Benzopyran-2-one,7-methoxy-8-(3-methyl-2-butenyl)-;7-Methoxy-8-isopentenylcoumarin;7-Methoxy-8-(3-methyl-2-butenyl)-coumarin;Osthol;Osthole;Ostol;Ostole.

 Acute toxicity(LD50):

 LD50-Lethal dose,50 percent kill.Oral.Rodent-rat.2905mg/kg.
 Behavioral:convulsions or effect on seizure threshold.
 Behavioral:muscle contraction or spasticity.
 Lungs,Thorax,or Respiration-dyspnea.
 Reference:IJMRAQ Indian Journal of Medical Research.(Indian Council of Medicial Research,Ansari Nagar,New Delhi 110 029,India) V.1-1913-Volume(issue)/page/year:55,241,1967.

 LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-rat.600mg/kg.
 Toxic effects:
 Behavioral:convulsions or effect on seizure threshold.
 Behavioral:muscle contraction or spasticity.
 Lungs,Thorax,or Respiration-dyspne.
 Reference:IJMRAQ Indian Journal of Medical Research.(Indian Council of Medicial Research,Ansari Nagar,New Delhi 110 029,India) V.1-1913-Volume(issue)/page/year:55,241,1967.

 LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-mouse.190mg/kg.
 Toxic effects:
 Behavioral:convulsions or effect on seizure threshold.
 Behavioral:muscle contraction or spasticity.
 Lungs,Thorax,or Respiration-dyspne.
 Reference:IJMRAQ Indian Journal of Medical Research.(Indian Council of Medicial Research,Ansari Nagar,New Delhi 110 029,India) V.1-1913-Volume(issue)/page/year:55,241,1967.

 LD50-Lethal dose,50 percent kill.Subcutaneous.Rodent-mouse.16mg/kg.
 Details of toxic effects not reported other than lethal dose value.
 Reference:PCJOAU Pharmaceutical Chemistry Journal(English Translation).Trnaslation of KHFZAN.(Plenum Pub.Corp.,233 Spring St.,New York,NY 10013)nO.1-1967-Volume(issue)/page/year:11,331,1977.

 LD50-Lethal dose,50 percent kill.Intravenous.Mammal-dog. >40mg/kg.
 Details of toxic effects not reported other than lethal dose value.
 Reference:AIPTAK Archives Internationales de Pharmacodynamie et de Therapie.(Heymans Institute of Pharmacology,De Pintelaan 185,B-9000 Ghent,Belgium) V.4-1898-Volume(issue)/page/year:150,425,1964.

 LD50-Lethal dose,50 percent kill.Subcutaneous.Rodent-rabbit. >70mg/kg.
 Details of toxic effects not reported other than lethal dose value.
 Reference:AIPTAK Archives Internationales de Pharmacodynamie et de Therapie.(Heymans Institute of Pharmacology,De Pintelaan 185,B-9000 Ghent,Belgium) V.4-1898-Volume(issue)/page/year:138,400,1962.

 LDLo-Lowest published lethal dose.Intravenous.Rodent-rabbit.25mg/kg.
 Toxic effects:
 Behavioral:convulsions or effect on seizure threshold.
 Lungs,Thorax,or Respiration-respiratory stimulation.
 Lungs,Thorax,or Respiration-other changes.
 Reference:AIPTAK Archives Internationales de Pharmacodynamie et de Therapie.(Heymans Institute of Pharmacology,De Pintelaan 185,B-9000 Ghent,Belgium) V.4-1898-Volume(issue)/page/year:138,400,1962.

 LD50-Lethal dose,50 percent kill.Oral.Rodent-guinea pig. >1 gm/kg.
 Details of toxic effects not reported other than lethal dose value.
 Reference:AIPTAK Archives Internationales de Pharmacodynamie et de Therapie.(Heymans Institute of Pharmacology,De Pintelaan 185,B-9000 Ghent,Belgium) V.4-1898-Volume(issue)/page/year:150,425,1964.

Reference:

• 1.What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:08th,Oct.2010.