Silymarin.Milk Thistle and applications.
- Botanical Basic Data of Milk Thistle.
- Phytochemicals of milk thistle.
- History of Silymarin and foundation.
- Modern Application and function of Silymarin and silybin.
- Dosage and Administration.
- Milk Thistle:Pharmacology.
- The Awesome Power of the Milk Thistle.
- How Search engine think about Milk Thistle.
- Research Update of Silybum Marianum.Silymarin
- Photo Gallery of Silybum marianum.
A number of studies have suggested that silymarin is an anti-inflammatory. It regulates inflammatory mediators such as tumor necrosis factor (TNF), TNF-alpha, nitrous oxide, interleukin-, and interleukin-1 receptor antagonist. Silymarin also increases lymphocyte proliferation, interferon gamma, interleukin-, and interleukin- cytokines, in a dose-dependent manner. Taken together, these effects suggest a possible role in preventing or treating infectious disease.
Several mechanisms of cytoprotection have been identified. In some studies, milk thistle promoted neuronal differentiation and survival. In others, silymarin inhibited leukotriene formation by Kupffer cells and increased expression of growth factor beta-1 and c-myc.In animal studies, it has shown protective effects against damage to the pancreas from cyclosporine (Sandimmune); damage to the kidney from acetaminophen, cisplatin (Platinol), and vincristine (Oncovin); and damage to the liver from carbon tetrachloride, partly by reducing lipid peroxidation. In another study, silymarin slowed the progression of alcohol-induced liver fibrosis in baboons. In vitro and animal studies support the possibility that milk thistle has anticarcinogenic effects for cancers of the prostate, breast, skin, colon, tongue, and bladder.
- Silymarin.Milk Thistle and applications.
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