Ursolic acid:Actions,Commonly Known Benefit and Research.

Contents

• Basic Chemical Info.
• Basic Introduction and Botanical Info.
• Actions and Chemistry of Ursolic Acid.
• Commonly Known Benefit of Ursolic Acid.
• Pentacyclic Triterpenes (PCTs) as Inhibitors of Inflammation.
• Safety and Toxicity for Ursolic Acid.
• Administration and Dosage.
• Research Update of Ursolic acid.
• Photo Gallery of Ursolic acid Botanical Source

Actions and Chemistry of Ursolic Acid.:

Medicinal plants containing ursolic acid have been used in folk medicine before it was known which constituents were responsible for their therapeutic effectiveness. Contemporary scientific research which led to the isolation and identification of ursolic acid revealed and confirmed that several pharmacological effects, such as, anti-tumor, hepatoprotective, anti-inflammatory (oral and topical), anti-ulcer, antimicrobial, anti-hyperlipidemic and antiviral, can be attributed to ursolic acid.

 However, its anti-inflammatory (topical), anti-tumor (skin cancer), and antimicrobial properties are pertinent to the cosmetic industry.

 Ursolic acid has medicinally action, both topically and internally. Ursolic acid is used in many cosmetic preparations for its anti-inflammatory, antitumor and antimicrobial properties.

 Ursolic acid has antibacterial and antifungal activity. Tests have shown that Ursolic acid inhibits the growth of Candida albicans and Microsporium lenosum.
 Ursolic acid has anti-inflammatory properties and is used in ointments to treat burns.
 Topical application of ursolic acid inhibited TPA-induced initiation and promotion of tumor growth.
 

 Chemistry:

 Ursolic acid [(3Beta)-3-Hydroxyurs-12-en-28-oic acid] rarely occurs without its isomer oleanolic acid [(3Beta)-3-Hydroxyolean-12-en-28-oic acid] They may occur in their free acid form, as shown in Figure 1, or as aglycones for triterpenoid saponins which are comprised of a triterpenoid aglycone linked to one or more sugar moieties. Ursolic and oleanolic acids are similar in pharmacological activity.

 Several ursolic acid derivatives, both natural and synthetic, have been reported. Novel ursolic acid derivatives, including ursane-type triterpenoid saponins, naturally occur as secondary metabolites through complex metabolic processes in different parts of the plants. Synthetic derivatives obtained from ursolic acid have been reported and evaluated for their pharmacological action

Reference:

• Ursolic acid:Actions,Commonly Known Benefit and Research.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:08th,Oct.2010.