Wolfberry and Wolfberry extract.

4.8.Wolfberry Extracts as good kidney remedy.:

Barbary Wolfberry Extract.Wolfberry Polysaccharides.LBP.Lycium barbarum L.Lycium Berry extract.Lycii Berries photo picture image Wolfberry contain many useful nutritions,including Wolfberry polysaccharides,zeaxanthine,physalein,Ascorbic acid,Carotene,Riboflavin,Vitamine C,etc, all these substances are good natural antioxidant,and best function as anti-inflammation,anti-infection,and so many good natural antioxidant make wolfberry the best body energy remedy, taste fitful amount of wolfberry or wolfberry extracts could be good for: increase blood flow, increase blood vessel elasticity,decrease thrombus and blood aggregation,this could be good for heart,liver,kidney and other organs of human body,also increase sexual ability.

Hypoglycemic,hypolipidemic effects and diabetic treatment:

Persistent hypoglycaemic effects had been observed from Lycium shawii from some egyptian study experiment of diabetic rats (3.).Some relative study find that Lycium barbarum polysaccharide had protective effects on alloxan-induced isolated rat islet ceus damage in vitro,LBP can inhibite the significant decrease in SOD activity and a increase in MDA production which induced by Alloxan(43.).

Some alloxan-induced diabetic or hyperlipidemic rabbits test with Lycium barbarum fruit water decoction, crude polysaccharide extracts (crude LBP), and purified polysaccharide fractions (LBP-X) proposed that Lycium barbarum polysaccharides (glycocojugates), containing several monosaccharides and 17 amino acids, were major bioactive constituents of hypoglycemic effect. Both polysaccharides and vitamin antioxidants from Lycium barbarum fruits were possible active principles of hypolipidemic effect.The possible mechanism got explained that Hypoglycemic effect of LBP-X was more significant than those of water decoction and crude LBP, but its hypolipidemic effect seemed to be weaker. Total antioxidant capacity assay showed that all three Lycium barbarum extracts/fractions possessed antioxidant activity. However, water and methanolc fruit extracts and crude polysaccharide extracts exhibited stronger antioxidant activity than purified polysaccharide fractions because crude extracts were identified to be rich in antioxidants (e.g., carotenoids, riboflavin, ascorbic acid, thiamine, nicotinic acid)(76.). Some relative study about LBP onthe improvement of insulin resistance and lipid concluded LBP can ameliorate insulin resistance, and the mechanism may be involved in increasing cell-surface level of GLUT4, improving GLUT4 trafficking and intracellular insulin signaling. Some mechanism explain briefly noted LBP treatment for 3 weeks resulted in a significant decrease in the concentration of plasma triglyceride and weight in NIDDM rats. Furthermore, LBP markedly decreased the plasma cholesterol levels and fasting plasma insulin levels, and the postprandial glucose level at 30 min during oral glucose tolerance test and significantly increased the Insulin Sensitive Index in NIDDM rats. Lycium barbarum is one of the traditional oriental medicines. It has been reported to reduce blood glucose levels(95.).Some relative study about LBP on blood glucose, oxidative stress and DNA damage in rats with non-insulin dependent diabetes mellitus (NIDDM),some mechanism of related proposed LBP LBP can control blood glucose and modulate the metabolism of glucose, leading to significant improvement of oxidative stress markers (SOD, MDA) in rats with NIDDM. And that, LBP decreases DNA damage possibly via a decrease in oxidative stress levels.Suggest its supplement prevent the development of complications or even tendency to carcinogenesis in NIDDM rats(100.).Some STZ-induced diabetic rats experiment suggest Treated diabetic rats were administrated with LBP in drinking water through oral gavage for 30 days,results show that administration of LBP can restore abnormal oxidative indice near normal levels. Therefore, we may assume that LBP is effective in the protection of liver and kidney tissue from the damage of STZ-induced diabetic rats and that the LBP may be of use as a antihyperglycemia agent(108.).Some combinative study on type 2 diabetes mellitus proposed an herbal formulation consisting of the aqueous extracts of Radix Astragali, Radix Codonopsis and Cortex Lycii(wolfberry root bark) treatment resulted in significant enhancement of survival rate of rat pancreatic beta-cells which were treated by streptozotocin.For the background,Hyperglycemia is one of the main causes of oxidative stress in type 2 diabetes mellitus. During hyperglycemia, the increased level of various reducing sugars in the blood enhances the production of reactive oxygen species (ROS) and triggers tissue damage, especially in pancreatic beta-cells(118.,some similar relative study proposed this combination treatment did not exhibit any toxic effect to the host,activities and expression of antioxidant enzymes, catalase and superoxide dismutase, were up-regulated,128.).Relative alloxan-induced diabetic mice study treatment with Cortex Lycii Radicis (CLR) find CLR has hypoglycemic potential and could be useful in diabetes therapy,it mechanism can be simply explained that CLR alleviates the blood glucose and lipid increases associated with diabetes and improves the abnormal glucose metabolism and increases insulin secretion by restoring impaired pancrease beta-cells in alloxan-induced diabetic mice. Dosage identified as low and high in the test,for the traditional applications,Cortex Lycii Radicis (CLR) has been used as a traditional Oriental medicine as an antipyretic and to treat pneumonia, night-sweats, cough, hematemesis, inflammation, and diabetes mellitus for centuries(119.).In a streptozotocin-induced diabetic rat model study its result proposed Diabetic rats treated with LBP-4 (10 mg/kg) for 8 weeks showed increased activity of antioxidant enzymes and increased scavenging of oxygen radicals, while the activity of PKC in the renal cortex was maintained at a physiological level. The decreased activation of ERK1/2 in mesangial cells, through the involvement of PKC, could explain the protective mechanism in kidneys of diabetic rats treated with LBP-4.Oxidative stress is implicated in the pathogenesis of diabetic nephropathy(DN)(140.).

img Infertility photo picture image

Infertility treatment and its mechanisms:Lycium barbarum L. (Solanaceae) is a Chinese medicinal plant whose fruits (Fructus Lycii) are used by Chinese physicians for treatment of infertility.Some study findings proposed that Lycium's fertility-facilitating effects lay on a mechanism related:Fructus Lycii polysaccharides (FLPS) is a potent inhibitor of ultraviolet light-induced lipid peroxidation, and cytochrome c reduction by free radicals,demonstrate the protective effect of FLPS on time- and hyperthermia-induced testicular degeneration in vitro, indicate the potential mechanism of action for this protective effect.Oxidative stress was reported to be a major cause of structural degradation and apoptosis in hyperthermic testes, and thus the protective effect of FLPS could implicate an antioxidant mechanism of action(41.).Except man,for women with problems of infertility come from premature ovarian failure (POF),a traditional recipes composed of 10 herbs(a modification and extracts type of ancient remedy named Zuo-gui-wan,composed of concentrated herbal extracts of cooked rehmannia, Chinese yam, wolfberry fruit, dogwood fruit, cyathula root, dodder seed, antler glue, tortoise-plastron glue, epimedium and morinda root) got find can restored ovarian function effectively and promptly, and offers another option for treating infertility in patients with POF.Some mechanism got discussed breifly(60.).Some mice testicular tissue study proposed LBP provided a protective effect against the testicular tissue damage induced by heat exposure.More detailed mechanism explained as "When compared with negative control, a suitable concentration of LBP significantly increased testis and epididymis weights, improved superoxide dismutase (SOD) activity, and raised sexual hormone levels in the damaged rat testes. LBP had a dose-dependent protective effect against DNA oxidative damage of mouse testicular cells induced by H2O2. LBP improved the copulatory performance and reproductive function of hemicastrated male rats, such as shortened penis erection latency and mount latency, regulated secretion of sexual hormones and increased hormone levels, raised accessory sexual organ weights, and improved sperm quantity and quality."The present findings support the folk reputation of L. barbarum fruits as an aphrodisiac and fertility-facilitating agent, and provide scientific evidence for a basis for the extensive use of L. barbarum fruits as a traditional remedy for male infertility in China(98.).Some combination study on Sertoli cells in the rat testis proposed that Fructus Lycii, Radix Astragali and the combined administration of the two could promote and protect INHbetaB mRNA in Sertoli cells in vitro.
Lycium fruit has been given to treat sexual impotence. It was reported that by taking lycium fruit orally and in the form of an alcohol extract, it could markedly increase androgen levels in the blood, making patients feel more energetic. It is likely that sitosterols or terpenoids are responsible for this effect. The daily dosage of lycium fruit needed to obtain these effects is about 10 grams/day.

Reference:

1.Wolfberry and Wolfberry extract.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:09th,Oct.2010.