Wolfberry and Wolfberry extract.
- Basic Character and identification of Wolfberry.
- Plant Description of Wolfberry.
- Stem Cultivation,Seed reproduce,Fruit Preparation and Root Preparation of wolfberry.
- PhytoChemical Content of chinese wolfberry.
- Application and General Value of Wolfberry:
- 1.Character and Efficacy of chinese wolfberry.
- 2.Constituents and Pharmacology of wolfberry.
- 3.Ancient Medicine for Overall Wellbeing.
- 4.Natural Multi-nutrients of chinese wolfberry.
- 5.Function of Wolfberry Extracts and Wolfberry polysaccharides.
- 6.Wolfberry Extracts as good tumor inhibitor:Cancer prevention.
- 7.Wolfberry Extracts as good old man remedy.
- 8.Wolfberry Extracts as good kidney remedy.
- 9.Ancient literature registered wolfberry as a kind of herb medicine for anti-age.
- 10.Liver protection of Wolfberry Extracts.
- 11.Wolfberry and wolfberry extracts act as good remedy for hairdressing and skin care.
- 12.Wolfberry as good Hemopoiesis promoter.
- 13.Vision improvement function of wolfberry and wolfberry extracts.
- 14.Cholesterol reducer of wolfberry and wolfberry extracts.
- 15.Anti-aging function of wolfberry and wolfberry extracts.
- Functional Dosages of chinese wolfberry.
- Functional common taken method of chinese wolfberry.
- Safety and Acute Toxicity of LBP and LbGp.
- Where to source the best quality Chinese Wolfberry?
- How Search engine think about lycium?
- Wolfberry:Research Update
- Photo Gallery of Lycium barbarum.
4.9.Ancient literature registered wolfberry as a kind of herb medicine for anti-age.:
Wolfberry could make energy full,blood enough,Growth of Yang and Yin, decrease rheumatism,act as topmost herb remedy.
Ben Cao Hui Yan
Wolfberry taste bitter and cold,cure inside evil disease, warm heart and kidney,decrease thirsty,long taste stick bone, good for body and keep young.
Shen Nong Ben Cao Jing
Wolfberry long taking good and make energy full,make skin good appearance,wise brain and good for eyes,make spirit active,also prolong life.
Ben Cao Gang Mu
Wolfberry good for liver and kidney fill,increase sperm and make eyes clear,good for cure waist and knee ache,weak and short of sperm,inside fever and thirsty.
All these good character added up make wolfberry a good herb medicine for anti-oldness, diabetes,high choleaterol,liver disease,gastritis and other disease such as anti-tumor,increase white blood cell.
9.Anti-aging:some D-gal;actose induced mouse aging model test propopsed treatment via Lycium barbarum polysaccharide(or and Achyranthes bidentata polysaccharide)both decreased levels of serum AGE, hydroxyproline concentration in mouse skin and spontaneous motor activity in D-galactose;and enhance the lymphocyte proliferation and IL-2 activity, learning and memory abilities, SOD activity of erythrocytes,the test proposed ABP and LBP could inhibit nonenzyme glycation in D-galactose induced mouse aging model in vivo and ABP(Achyranthes bidentata polysaccharide) has a better inhibiting effect than LBP(64.).Some aging-youth 2BS fusion cells study proposed that Wolfberry fruit (WB) and Epimedium (EM) can accelerate the DNA synthesis rate of the aging youth 2BS fusion cells and prolong the life span of 2BS cells(66.). Some relative study about anti-aging effects of wolfberry suggested it exhibit neuroprotective effects against toxins in aging-related neurodegenerative diseases,the extracts got find elicited a typical dose-dependent neuroprotective effect against toxicity of fibrillar Abeta(1-42) and Abeta(25-35) fragments.As aged population dramatically increases in these decades, efforts should be made on the intervention for curing age-associated neurodegenerative diseases such as Alzheimer's disease (AD). Natural plant extracts of Lycium barbarum are well-known to exhibit anti-aging effects(91.).Some investigative study find arabinogalactan-protein (LBP-III) isolated from LBP markedly reduced the phosphorylation of PKR triggered by A beta peptide.Since the phosphorylation state of PKR increased with age, reduction of its phosphorylation triggered by A beta peptide may implicate that LBP-III from Fructus lycii is a potential neuroprotective agent in AD.Alzheimer's disease (AD) is an age-related neurodegenerative disease(115.).Some experiment concluded Polysaccharides extracted from L. barbarum can protect neurons against beta-amyloid peptide toxicity in neuronal cell cultures, and retinal ganglion cells in an experimental model of glaucoma. Valuable components of L. barbarum are not limited to its colored components containing zeaxanthin and carotene, but include the polysaccharides and small molecules such as betaine, cerebroside, beta-sitosterol, p-coumaric, and various vitamins(117.).Some Hcy-induced neuronal damage study proposed LBA exerted neuroprotective effects on cortical neurons exposed to Hcy with detailed data,suggest LBA has the potential to be a diseasemodifying agent for the prevention of AD,for the background,elevated plasma homocysteine (Hcy) level are thought increased the risk of Alzheime's disease (AD),and Hcy are thought damages neurons by inducing apoptosis, DNA fragmentation, and tau hyperphosphorylation(146.,150.).
Aging is a universal biological process that leads to progressive and deleterious changes in organisms. From ancient time, mankind has already interested in preventing and keeping ourselves young. Anti-aging study is certainly not a new research area. Nowadays, the meaning of anti-aging has been changed from simply prolonging lifespan to increasing health span, which emphasizes more on the quality of life. This is the concept of healthy aging and prevention of pathological aging, which is associated with diseases. Keeping our brain functions as in young age is an important task for neuroscientists to prevent aging-associated neurological disorders, such as Alzheimer's diseases (AD) and Parkinson's disease (PD). Neurodegenerative diseases can be cross-linked with a number of aging-associated conditions.The characteristics of medicinal herbs, especially their applications in different disease stages (prevention and intervention) and multi-targets properties, allow them to be potential anti-aging intervention in prevention and treatment of the aging-associated neurological disorders.
9.1.Prevent neurological diseases:some relative screening study about treatment of neurodegenerative diseases from 27 kinds of herb identified some herbs as candidate for delaying the progressive degeneration caused by neurological diseases,50% aqueous methanol extracts of four active extracts, Arisaema amurense, Lilium brownii var. colchesteri, Lycium chinense, and Uncaria rhynchophylla, exhibited the best activity and selectivity towards MAO-B with IC50 values of 0.44, 0.29, 0.40, and 0.03 mg/ml, respectively.for the background,Monoamine oxidase (MAO) catalyzes the oxidative deamination of biogenic amines accompaned by the release of H2O2. Two subtypes, MAO-A and MAO-B, exist on the basis of their specificities to substrates and inhibitors. The regulation of MAO-B activity is important in the treatment of neurodegenerative diseases(65.).Some relative study proposed extract from L. barbarum is not simply an anti-oxidant in order to function as a neuroprotective agent,its neurons protective mechanisms not only dependent on anti-oxidative effects,LBG also exhibits cytoprotective effects against reducing stress by lowering the DTT-induced LDH release and caspase-3 activity,thus cytoprotective effects against reducing stress by DTT also calculated as one compositive mechanism of its neuron protective mechanisms(101.).Some relative study on alkaline extract of Lycium barbarum suggested the alkaline extract exerts different biological mechanisms to protect neurons,and concluded the glycoconjugate isolated from novel alkaline extraction method can open up a new avenue for drug discovery in neurodegenerative diseases(114.).Relative study identified fraction of polysaccharide from Wolfberry (LBA) exerted significant neuroprotective effects on cultured cortical neurons exposed to glutamate,Glutamate excitotoxicity is involved in many neurodegenerative diseases including Alzheimer's disease (AD). Attenuation of glutamate toxicity is one of the therapeutic strategies for AD(136.).
- 1.Wolfberry and Wolfberry extract.
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