Gentian root.Gentiana Lutea.Chinese Gentian.

Contents

• Botanical Data of Radix Gentianae.
• Description of Gentian:Narrative and Names of Gentian,Collection of Gentian,Actions and indication of Gentian.
• Active constituents of Gentian.Radix Gentianae.Gentian root.
• Properties of Gentian.Radix Gentianae.Gentian root.
• Medicinal Action and application of Gentian.Radix Gentianae.Gentian root.
• Therapeutics and Pharmacology of Gentian.Radix Gentianae.Gentian root.
• Suggestion and Administration of Gentian.Radix Gentianae.Gentian root.
• Application case study:Inner Purity Formulation with Gentian.
• How Search engine think about Gentian.
• Research Update:Gentian.
• Photo Gallery of Gentiana.

Medicinal Action and application of Gentian.Radix Gentianae.Gentian root.:

Primary Uses:Appetite Loss, Circulation/poor, Gastric Disorders, Indigestion, Jaundice, Liver Disorders

 Secondary Uses:Anemia, Blood Impurities, Colds, Constipation, Cramps/stomach, Diarrhea, Dysentery, Fevers, Gas, Gout, heartburn, Menstruation/absent, Nausea, Spleen Ailments, Urinary Problems, Worms, Wounds, Yeast Infections

 Medicinal virtues:The virtues of both are similar. They resist putrefactions and poison and a more sure remedy to prevent the pestilence cannot be found. It strengthens the stomach, helps digestion, comforts the heart, and preserves it against Paintings and swoonings. The powdered dried root opens obstructions of the liver and restores the appetite.

 The herb provokes urine and the terms exceedingly, and therefore should not be given to women with child. But it is profitable for those troubled with cramps and convulsions, to drink the decoction. This also breaks the stone and helps ruptures. To kill the worms, take half a dram (1g) of the powder in the morning in any convenient liquor. It will also instantly heal lites on cattle's udders.

 Gentian (Gentiana lutea) Gentian has been used for centuries for weakened digestive ability due to a weakness in gastric secretion, bile production or pancreatic enzyme production. It is our standard treatment for loss of appetite, anorexia, flatulence and heartburn. It also is great for sugar cravings along with Gymnema. Its bitterness really increases salivation and vagal nerve function, so we've successfully used it for people who have lost bowel function due to sluggish vagal nerve function.

 Actions:The essential active principles are the bitter substances contained in the herb. These bring about a reflex excitation of the taste receptors, leading to increased secretion of saliva and the digestive juices. Gentian root is therefore considered to be not simply a pure bitter, but also a roborant and tonic. In animal experimentation there are indications that bronchial secretion is increased.


 Anti-inflammatory and anti-allergic effect:Gentiopicroside can inhibit carrageenin from causing edema in rat paws. Intra-abdominal injection of gentianine has a significant inhibitory effect on egg white and formaldehyde-induced edema in rats. Gentian also has a significant anti-allergic effect. Experiments show that gentiopicroside has a significant protective effect on histamine-induced shock in guinea pigs and on egg white-induced allergic shock in rats. It can also significantly reduce capillary permeability in rats. If gentian water-extract is given before allergy was induced or before and after an allergic reaction attack, it can, like cortical hormone, significantly inhibit picryl chloride-induced DTH in mice.

 Anti-pathogenic effects:In vitro experiments show that Long Dan decoction can inhibit Pseudomonas aeruginosa, Bacillus proteus, typhoid bacillus, Staphylococcus aureus, Trichophyton gypseum, and Nocardia asteroides. The decoction has a strong paralytic effect on Ascaris suis. Fed to cats at 75-200mg/kg, gentianine can expel ascaris.

 Assimilation of fats:Gentian's bitter glycosides gentiopicrin and amarogentin stimulate secretion of saliva in the mouth and hydrochloric acid in the stomach, and may also stimulate bile production, which aids in the body's assimilation of fats.

 Gentian is one of the most useful of our bitter vegetable tonics. It is specially useful in states of exhaustion from chronic disease and in all cases of general debility, weakness of the digestive organs and want of appetite. It is one of the best strengtheners of the human system, and is an excellent tonic to combine with a purgative to prevent its debilitating effects. Many dyspeptic complaints are more effectually relieved by Gentian bitters than by Peruvian Bark. It is of extreme value in jaundice and is prescribed extensively.

 Besides being unrivalled as a stomachic tonic, Gentian possesses febrifuge, emmenagogue, anthelmintic and antiseptic properties, and is also useful in hysteria, female weakness, etc. Gentian with equal parts of Tormentil or galls has been used with success for curing intermittent fever.

 As a simple bitter, Gentian is considered more palatable combined with an aromatic, and for this purpose orange peel is frequently used. A tincture made with 2 oz. of the root, 1 oz. of dried orange peel, and ? oz. bruised cardamom seeds in a quart of brandy is an excellent stomachic tonic, and is efficacious in restoring appetite and promoting digestion. A favourite form in which Gentian has been administered in country remedies is as an ingredient in the so-called Stockton bitters, in which Gentian and the root of Sweet Flag play the principal part.
 


 Cholagogic effects:Administered to dogs by IV injection, Long Dan juice can significantly increase the bile flow. Specifically, the bile flow peaks at the 5-minute and 20-minute marks, the former due to gallbladder contraction, while the latter due to an increase in bile secretion. Administered by intraduodenal injection to healthy rats or rats with live damages, Long Dan juice has a significant cholagogic effect, increasing bile secretion, and promoting gallbladder contraction.

 Cooling the system:Gentian is used to reduce fevers by cooling the system. Gentian contains a bitter principle, amarogentin , which stimulates the glands, including the adrenals and the thyroid. It helps in the production of bile, which can have a positive effect on the liver and gallbladder.

 Gentian is also used to clean the bowels, stimulate the pancreas, stimulate circulation, aid in the digestive process and help with female problems. Historically, gentian has been used to treat wounds and taken internally for inflammation from arthritis, jaundice and a sore throat. It is considered a great tonic for strengthening the entire body.
 Gentian root Strengthens the digestive organs, increases circulation and is good for female organs.
 Gentian root is a stimulator of the general circulation, which in turn stregthens the total system.

 Gentian root is a high in simple energy producing sugars and is beneficial to the digesting organs, the stomach, and pancreas, as well as being an aid to the well being of both the kidney and spleen.

 Gentian root Anti-inflammatory used in treatment of arthritis
 

 Widespread use of gentian as an appetite stimulant and digestive aid would seem to favor the herb as effective for these conditions. However, since it is normally consumed as an alcoholic beverage, it is difficult to separate the effects of gentian from those of alcohol, which are very similar, at least when the alcohol is consumed in moderate amounts. In normal individuals, gentian is unlikely to produce undesirable side effects; however, occasional headaches have been reported. Overdoses (greater than 0.1 to 2 g of the drug decocted in 150 ml of water, three times per day), could lead to nausea or vomiting. Use is contraindicated in gastric or duodenal ulcers and hyperacidity. Pahlow warns that the drug may not be tolerated well by those with very high blood pressure or by expectant mothers. Actually, these people should be very cautious about using any medication, herbal or otherwise.


 Digestive aids and Chronic disease:Gentian root and other highly bitter plants have been used for centuries by herbalists in Europe as digestive aids (the well-known Swedish bitters often contain gentian). Other folk uses included topical application on skin tumors, decreasing fevers, and treatment of diarrhea.

 Gentian increases the appetite, stimulates digestive juices, decreases intestinal inflammation, treats indigestion, heartburn, liver and spleen disorders, promotes menstruation, strengthens and builds the body, and is helpful for gout and arthritis. Do not use during pregnancy.

 Gentian is one of the most useful of our bitter vegetable tonics. It is specially useful in states of exhaustion from chronic disease and in all cases of general debility, weakness of the digestive organs and want of appetite. It is one of the best strengtheners of the human system, and is an excellent tonic to combine with a purgative to prevent its debilitating effects. Many dyspeptic complaints are more effectually relieved by Gentian bitters than by Peruvian Bark. It is of extreme value in jaundice and is prescribed extensively.

 Effect on the central nervous system:Gentianine has significant sedative and anti-convulsion effects, and it can significantly reduce body temperature. Experiments show that gentianine can significantly reduce spontaneous activity in animals, strengthen the anesthetic effect of barbital and chloral hydrate on the central nervous system, and inhibit strychnine-induced convulsion. It does not inhibit cardiazol-induced convulsion, however, and it can aggravate nicotine-induced convulsion. Intra-abdominal injection of swertiamarin can also inhibit mice's spontaneous activity, and prolong the duration of sodium pentothal's anesthetic effect. Hot plate and body torsion experiments on mice show that intra-abdominal injection of swertiamarin has a significant analgesic effect. At 600mg/kg, its analgesic effect is about the same as that of morphine at 10mg/kg.

 Effect on the activity of steroid 4-reductase:Gentian root can significantly inhibit the activivity of 4-reductase of steroid, a key enzyme for the decomposition and metabolism of cortisol in the liver of rats with hyperthyroidism, thus reducing the degradation of cortisol and significantly decreasing the excretion of 17-hydroxy corticosteroid.

 Inhibitory effect on reductase of crystal aldose:Gentian root has a significant inhibitory effect on reductase (AR) of crystal aldose in rats.

 Protecting the liver:Administered to mice by abdominal injection at 30mg/kg, Long Dan juice can alleviate CCl4-induced cytomorphosis and tissue necrosis, and increase the content of hepatic glycogen. Administered to mice by abdominal injection at 240mg/kg, twice a day, for two days, gentiopicroside can counteract CCl4- or GALN-induced liver damages. Gentiopicroside can also significantly reduce liver lipid peroxidation in hungry mice. Sweroside can significantly counteract CCl4- or GALN-induced acute liver damages in both mice and rats, reduce ALT, AST, and ALP, and prevent splenomegaly caused by GALN poisoning.


 Stomach-strengthening effect:Direct perfusion of gentiopicroside through gastric fistula to the stomach of dogs can increase the secretion of gastric juice and free acid. Administering by rubbing it onto the underside of the tongue or through intravenous injection, however, does not have this effect, suggesting that the effect is due to direct action on the stomach. Swertiamarin can significantly alleviate spasm in isolated small intestine of rabbits, guinea pigs, or rats, and can antagonize the stimulatory effect of acetylcholine, histamine, and barium chloride on isolated small intestine of guinea pigs.

 Other Uses of Gentian:

 Orally, Long Dan Cao/Gentian is used for digestive disorders, such as loss of appetite, fullness, and flatulence. It is used orally for fever, for hysteria, to stimulate menstrual flow, as an anthelmintic, and antiseptic.
 Topically, Long Dan Cao/Gentian is used for treating wounds and cancer.

 Combination with European elder flower, verbena, cowslip flower, and sorrel, gentian is used orally for maintaining healthy sinuses and treating sinusitis. It is used in combination with other products for malaria.
 In traditional medicine, Long Dan Cao/Gentian has been used orally for diarrhea, gastritis, heartburn, and vomiting.
 Foods and Beverages, Long Dan Cao/Gentian is used as an ingredient.
 In manufacturing, Long Dan Cao/Gentian is used in cosmetics.

Reference:

• 1.Gentian root.Gentiana Lutea.Chinese Gentian.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:11th,Oct.2010.