Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.

Contents

• Botanical Basic Data of Nettle.
• Plant Description of Nettle.Urtica dioica L....Spectrology and History of Nettle.
• Phytochemicals of Nettle.Urtica dioica L.,Urticae radix.
• Actions and Indications of Nettle.Urtica dioica L.,Urticae radix.
• Therapeutics and Pharmacology,Historical or traditional use of Nettle.
• Nettle Pharmacology:5 alpha-reductase inhibition.
• Nettle Pharmacology:Anti-inflammatory and immunomodulatory activity.
• Nettle Pharmacology:Antiviral activity.
• Nettle Pharmacology:Aromatase activity inhibition.
• Nettle Pharmacology:Cell proliferation inhibition.
• Nettle Pharmacology:Na+, K+-ATPase inhibition.
• Nettle Pharmacology:Other activities.
• Nettle Pharmacology:Pharmacodynamics/Kinetics.
• Mechanism and General Use of Nettle.
• Biological Activities and Clinical Research.
• Dosage,Safety and Suggestions of Nettle.
• Precautions and Possible Interactions.
• How Search Engine think about Nettle.
• Research Update:Nettle and Its Constituents.

Nettle Pharmacology:Cell proliferation inhibition.:

Urtica dioica directly inhibited cell proliferation and the binding of epidermal growth factor to its receptor in a tumor cell line. Subfractions of an aqueous ethanolic stinging nettle root extract inhibited growth of BPH-tissue in vitro; a methanolic extract suppressed proliferation of BPH-tissue ex vivo. This activity may contribute to anti-inflammatory and antiprostatic activity of the extracts. The polysaccharide fraction, of the 20% methanolic extract of stinging nettle roots, was able to reduce the induced growth of prostate gland by 33.8% in mice. Chronic intraperitoneal administration of Bazoton solution at a dose of 20mg per kilogram daily in male rats for 10 days had induced a reduction of prostate weight. A reduction of biological activity in prostate cells was noticed by fluorescent microscopy under the effect of extract of Radix urticae (ERU)-Bazoton in patients with benign prostatic hypertrophy.

 Interaction with sex hormone binding globulin (SHBG):SHBG appears to play a role in the regulation of prostate cells. A hydroethanolic root extract and a methanolic root extract interfered with the binding of dihydrotestosterone (DHT) with SHBG. An aqueous extract was able to inhibit the binding of SHBG to receptors on the membrane of human prostate cells.

Reference:

• 1.Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:12th,Oct.2010.