Application and Uses of Gymnema sylvestre and Gymnemic acid.
- Botanical Basic Information of Gymnema Sylvestre.
- Parts used and Habitat of Gymnema sylvestre.
- Phytochemicals,Constituents and Structure of Gymnema sylvestre.
- Application and Uses of Gymnema sylvestre and Gimnemic Acid.
- Gymnema:Diabetes,Lipid-lowering,Weight loss.
- Gymnema Herb:Administration Guide and Safety.
- Research Update:Gymnema and its derivatives.
Applications and Properties:
Diabetes:best known for its apparent ability to lower blood sugar levels,help control both type 1 and type 2 diabetes.
Clear heat and cool blood,
Expel pus and disperse swelling,
Relieve pains and grow muscles.
Mechanism Note:gymnemic acid mime glucose molecules,the glucose-like molecules in the gymnemic acid fill the receptor locations in the absorptive external layers of the intestine, thereby preventing the intestine from absorbing the sugar molecules. The direct evidence is that sugar taste no longer sweet when took with the gymnema. Gymnema sylvestre significantly reduces the metabolic effects of sugar by preventing the intestines from absorbing the sugar molecules during the process of digestion. Because there is a change in the absorption of sugar, there is a consequent change in the blood sugar level. Also, it has been shown in clinical trials to assist regeneration of the insulin-producing Beta Cells, thus reduces prescription insulin requirements for those diabetics who actively monitor blood sugar levels.
Indicated in Chinese medicine:Rheumatism pain,swelling and pain in throat,scrofula,acute mastitis,sore and furuncle,Skin tinea and eczema,innominate toxic swelling,venomous snake bite.
Indicated in Indian(Ayurvedic),African medicine:managing 'honey urine'(diabetes),other blood sugar disorders,preventing diabetes in individuals at high risk for the disorder or for managing metabolic control in general,weight-loss agent.
Dosage:antidiabetic effects have used 200 or 400 mg of an extract standardized to contain 25% gymnemic acids administered twice daily.
Safety and Toxicity:
The acute LD 50 was 3990 mg/kg. The safety ratio (LD 50 /ED 50 ) was 11 and 16 in normal and diabetic rats, respectively.
No adverse reactions were reported in a long-term study of insulin-dependent diabetic patients.
Will it harm you?what the studies say:On the basis of years of use in various countries with no reports of severe adverse reactions,it can be assumed that gymnema is relatively harmless.But keep in mind that well-designed and long-term toxicity studies have not been done.Also,diabetes is a serious condition that requires the care of a qualified physician;people with diabetes should consult their doctor before taking this herb,and always mention it in case it affects the medicines they are presently taking or lowers their blood sugar levels.
- 1.Application and Uses of Gymnema sylvestre and Gymnemic acid.
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