Application and Uses of Gymnema sylvestre and Gymnemic acid.
- Botanical Basic Data of Gymnema Sylvestre.
- Parts used and Habitat of Gymnema sylvestre.
- Phytochemicals and Structure of Gymnema sylvestre.
- Application and Uses of Gymnema sylvestre and Gimnemic Acid.
- Gymnema:Diabetes.Lipid-lowering.Weight loss.
- Gymnema and its administration.
- Research Update:Gymnema.
Applications and Properties:
Diabetes:best known for its apparent ability to lower blood sugar levels,help control both type 1 and type 2 diabetes.
Mechanism Note:gymnemic acid mime glucose molecules,the glucose-like molecules in the gymnemic acid fill the receptor locations in the absorptive external layers of the intestine, thereby preventing the intestine from absorbing the sugar molecules. The direct evidence is that sugar taste no longer sweet when took with the gymnema. Gymnema sylvestre significantly reduces the metabolic effects of sugar by preventing the intestines from absorbing the sugar molecules during the process of digestion. Because there is a change in the absorption of sugar, there is a consequent change in the blood sugar level. Also, it has been shown in clinical trials to assist regeneration of the insulin-producing Beta Cells, thus reduces prescription insulin requirements for those diabetics who actively monitor blood sugar levels.
Dosage: antidiabetic effects have used 200 or 400 mg of an extract standardized to contain 25% gymnemic acids administered twice daily.
Safety and Toxicity:
The acute LD 50 was 3990 mg/kg. The safety ratio (LD 50 /ED 50 ) was 11 and 16 in normal and diabetic rats, respectively.
No adverse reactions were reported in a long-term study of insulin-dependent diabetic patients.
- 1.Application and Uses of Gymnema sylvestre and Gymnemic acid.
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