Turmeric Root or Curcuma Root,Phytochemicals and Applications.

Contents

• Basic Botanical Data and Identification of Turmeric Root.Curcuma Root.
• Description of Turmeric Root.Curcuma Root.
• Origin of Curcuma root.
• Curcuma Root Appearance and characters.
• Powdered plant material of Curcuma Root.
• Chemical assays and Phytochemicals of Turmeric Root.Curcuma Root.
• Medicinal uses of Turmeric Root.Curcuma Root.
• Experimental pharmacology of Turmeric Root.Curcuma Root.
• Functions of Turmeric Root.Curcuma Root.
• Curcuma Root Suggestions and Administrations.
• Literature from Chinese historical sources:Curcuma Root.
• Modern Researches of Turmeric Root.Curcuma Root.
• Curcuma longa Common Application.
• Dose escalation of a curcuminoid formulation.
• Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury.
• Quality control including chromatographic fingerprint profiling.
• Research Update:Curcumae Longae.Curcuma longa.

Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury.:

Background: In the present investigation, the effect of Curcuma longa (Cl) and Ocimum sanctum (Os) on myocardial apoptosis and cardiac function was studied in an ischemia and reperfusion (I-R) model of myocardial injury.

 Methods: Wistar albino rats were divided into four groups and orally fed saline once daily (sham, control IR) or Cl (100 mg/kg; Cl-IR) or Os (75 mg/kg; Os-IR) respectively for 1 month. On the 31st day, in the rats of the control IR, Cl-IR and Os-IR groups LAD occlusion was undertaken for 45 min, and reperfusion was allowed for 1 h. The hemodynamic parameters{mean arterial pressure (MAP), heart rate (HR), left ventricular end-diastolic pressure (LVEDP), left ventricular peak positive (+) LVdP/dt (rate of pressure development) and negative (-) LVdP/dt (rate of pressure decline)} were monitored at pre-set points throughout the experimental duration and subsequently, the animals were sacrificed for immunohistopathological (Bax, Bcl-2 protein expression and TUNEL positivity) and histopathological studies.

 Results: Chronic treatment with Cl significantly reduced TUNEL positivity (p less than 0.05), Bax protein (p less than 0.001) and upregulated Bcl-2 (p less than 0.001) expression in comparison to control IR group. In addition, Cl demonstrated mitigating effects on several myocardial injury induced hemodynamic {(+)LVdP/dt, (-) LVdP/dt and LVEDP} and histopathological perturbations. Chronic Os treatment resulted in modest modulation of the hemodynamic alterations (MAP, LVEDP) but failed to demonstrate any significant antiapoptotic effects and prevent the histopathological alterations as compared to control IR group. CONCLUSION: In the present study, significant cardioprotection and functional recovery demonstrated by Cl may be attributed to its anti-apoptotic property. In contrast to Os, Cl may attenuate cell death due to apoptosis and prevent the impairment of cardiac performance.

Reference:

• 1.Turmeric Root or Curcuma Root,Phytochemicals and Applications.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:18th,Oct.2010.