What is Ox-Knee Root or Radix Achyranthis Bidentatae?

Pharmacology of Ox-knee root Constituents:Inokosterone and Ecdysterone.:

Ox-Knee Root Extract Achyranthes bidentata Bl Radix Achyranthis Bidentatae Twotooth Achyranthes Root Cyathula Root Chuan Niu Xi Szechwan Ox Knee Root Extract photo picture image Inokosterone:Pharmacology

Pupal abduction and Prompt ecdysis:Injection 0.05~5ug to worm of housefly,pupal abduction ratio 55% or higher,Injection 1 ug to silkworm pupa,ratio of silk moth change ratio in 14~20 days no less than 90%,Injection 0.5~2 ug to lobster prompt ecdysis.

Blood sugar control:Intraperitoneal Injection 0.1~10 mg/kg to Rat or Oral dose 1~100 mg/kg,show inhibition of high blood sugar of Rat caused by Glucgon.Reference:Zhi Wu Yao You Xiao Cheng Fen Shou Ce.1986.609,368.Jiang Jiwu,etc.published by Ren Min Wei Sheng Chu Ban She.

Protein Synthesis:Intraperitoneal Injection or Oral dose for mouse,show strong increase of amino acid synthesis into protein in liver.Reference:Zhong Yao Xian Dai Yan Jiu Yu Lin Chuang Ying Yong(Modern Research and Clinical Applications of TCM).by Yin Jiang,etc.published by Xue Yuan Chu Ban She.1993,169.

Toxicity: LD50,Lethal dose,Intraperitoneal injection.mouse.7.8 grams/kg.

Ecdysterone:Pharmacology

Lower Blood sugar and Choleterol:Edcysterone show effects on lowering blood sugar and cholesterol of animals.Reference:Zhi Wu Yao You Xiao Cheng Fen Shou Ce.1986.609,368.Jiang Jiwu,etc.published by Ren Min Wei Sheng Chu Ban She.

Protein Synthesis Prompt:Injection or Oral taken for mouse experiment proved that ecdysterone could increase volume of protein synthesis from amino acids in liver,and prompt RNA synthesis of karyon of liver cells.Continuous feed for young mouse 60 days make obvious body weight increase,and high level of protein synthesis capacity in liver and kidney.Keep support high activity of Infantile Cells,yet fail to recover depressed activity of mature cells.Reference:Zhong Yao Xian Dai Yan Jiu Yu Lin Chuang Ying Yong(Modern Research and Clinical Applications of TCM).by Yin Jiang,etc.published by Xue Yuan Chu Ban She.1993,169.

Toxicity:LD50,Lethal dose,Intraperitoneal injection.male mouse.6.4 grams/kg.LD50,Lethal dose,Oral.male mouse.>9 grams/kg.

Reference:

1.What is Ox-Knee Root or Radix Achyranthis Bidentatae?

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:18th,Oct.2010.