Ellagic Acid:Benzoaric acid.Elagostasine.Eleagic acid.:Introduction and Its Benefit Applications.Ellagic Acid.
Contents
Common Benefits of Ellagic Acid.:
Anti-Cancer:Antiproliferative and Antioxidant
Ellagic acid seems to have some anti-cancer properties. It can act as an antioxidant, and has been found to cause apoptosis (cell death) in cancer cells in the lab.There are also reports that ellagic acid may help the liver to break down or remove some cancer-causing substances from the blood.Some supporters have claimed these results mean that ellagic acid can prevent or treat cancer in humans. This has not been proven. Unfortunately, many substances showing promise against cancer in lab and animal studies have not been found to be useful in people.
Research in cell cultures and lab animals has found that ellagic acid may slow the growth of some tumors caused by certain carcinogens. While this is promising, at this time there is no reliable evidence from human studies showing that ellagic acid in any form can prevent or treat cancer.Further research is needed to determine what benefits it may have, although Professor Gary Stoner from Ohio State University, referring specially to dark (black and blue) raspberries (in combination with anthocyanins) registered a patent on June 23, 2005 relating to fighting cancers and their metastases with ellagic acid.
Ellagic acid has antiproliferative and antioxidant properties in a number of in vitro and small-animal models. The antiproliferative properties of ellagic acid are due to its ability to directly inhibit the DNA binding of certain carcinogens, including nitrosamines and polycyclic aromatic hydrocarbons. As with other polyphenol antioxidants, ellagic acid has a chemoprotective effect in cellular models by reducing oxidative stress.
These properties have generated interest in potential human health benefits from the consumption of ellagic acid. However, very little study of these proposed benefits has been reported as of 2008. A small randomized controlled trial involving 19 patients with carotid artery stenosis found that pomegranate juice, which is high in ellagic acid, appeared to reduce blood pressure and carotid artery wall thickness.A 2005 controlled study of 48 patients undergoing chemotherapy for prostate cancer found that ellagic acid supplementation reduced the rate of chemotherapy-associated neutropenia (though there were no cases of severe neutropenia in either the ellagic acid or control group). Ellagic acid supplementation did not improve overall or progression-free survival of patients with prostate cancer in this trial.
Despite the very preliminary state of evidence supporting health benefits in humans, ellagic acid has been marketed as a dietary supplement with a range of claimed benefits against cancer, heart disease, and other medical problems. Ellagic acid has been identified by the U.S. Food and Drug Administration as a "Fake Cancer Cure Consumers Should Avoid".A number of U.S.-based sellers of dietary supplements have been warned by the Food and Drug Administration for promoting ellagic acid with claims that violate the Federal Food, Drug, and Cosmetic Act.
Other Benefits:
Ellagic acid has also been said to reduce heart disease, birth defects, liver problems, and to promote wound healing. One 2004 study published in the journal Clinical Nutrition showed clearing of plaque from the carotid artery after three years of supplementation with pomegranate juice, which contains ellagic acid. There are few results from human studies regarding other claims at this time.
Reference:
-
- 1.Ellagic Acid:Benzoaric acid.Elagostasine.Eleagic acid.:Introduction and Its Benefit Applications.Ellagic Acid.
Article Information:
♥The article and literature was edited by herbalist of MDidea Extracts Professional.It runs a range of online descriptions about the titled herb and related phytochemicals,including comprehensive information related,summarized updating discoveries from findings of herbalists and clinical scientists from this field.The electronic data information published at our official website www.mdidea.com and www.mdidea.net,we tried best to update it to latest and exact as possible.
♣ last edit date:
