L-DOPA:L-Dihydroxyphenylalanine.:Introduction and Its Benefit Applications.
Contents
L-DOPA Natural sources.:
L-Dopa comes and rich in a traditional chinese herb named as Mucuna pruriens or Ci mao li dou,used as a minor food crop and medicinal bean in China and west Africa.
Biosynthesis:
L-DOPA is produced from the amino acid tyrosine by the enzyme tyrosine hydroxylase. It is also the precursor molecule for the catecholamine neurotransmitters dopamine and norepinephrine (noradrenaline), and the hormone epinephrine (adrenaline). Dopamine is formed by the decarboxylation of L-DOPA.
L-DOPA can be directly metabolized by catechol-O-methyl transferase (COMT) to 3-O-methyldopa (3-OMD) and then further to vanillactic acid (VLA). This metabolic pathway is non-existent in the healthy body but becomes important after peripheral L-DOPA administration in patients with Parkinson's Disease or in the rare cases of patients with aromatic L-amino acid decarboxylase (AADC) enzyme deficiency.
The prefix L- references its property of levorotation (compared with dextrorotation or D-DOPA).
Reference:
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- 1.L-DOPA:L-Dihydroxyphenylalanine.:Introduction and Its Benefit Applications.
This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.
♣ last edit date:28th,Oct.2010.
