Oligomeric Proanthocyanidins Introduction and Its Benefit Applications.

Contents

• Chemical Info:Oligomeric Proanthocyanidins.
• Introduction:Oligomeric Proanthocyanidins.
• Oligomeric Proanthocyanidins Discovery Story.
• Natural sources:Oligomeric Proanthocyanidins.
• Common Benefits of Oligomeric Proanthocyanidins.
• Oligomeric Proanthocyanidins Safety and Toxicity.
• Research Update:Oligomeric Proanthocyanidins.

Oligomeric Proanthocyanidins Safety and Toxicity.:

Acute toxicity(LD50):Grape Seed Extract.OPCs:
 LD50-Lethal dose,50 percent kill.Oral.Rodent-mouse.>4000 mg/kg.
 LD50-Lethal dose,50 percent kill.Oral.Rodent-rat.>4000 mg/kg.

 Chronic toxicity:Grape Seed Extract.OPCs:
 Chronic toxicity test.Oral.Dogs.Dose/Period:60 mg/kg/day.12 Months.No toxic effects.
 Chronic toxicity test.Oral.Rats.Dose/Period:60 mg/kg/day.6 Months.No toxic effects.

 Proanthocyanidins are almost completely non-toxic both in acute dosage (LD50>4,000 mg/kg in rats and mice) and high long-term dosage (no toxic effects at 60 mg/kg/day for 12 months in dogs and six months in rats). They have no potential for causing mutations or birth defects, and have no adverse effect on fertility, pregnancy, or nursing.

Reference:

• 1.Oligomeric Proanthocyanidins,OPCs:Introduction and Its Benefit Applications.

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:28th,Oct.2010.