What is Modified Citrus Pectin,MCP,an inhibitor of cancer metastasis and its wide uses?

Contents

• FAQ:Modified Citrus Pectin (MCP).
• Brief Introduction:Modified Citrus Pectin.
• What is Modified Citrus Pectin?.
• What is Galacturonic acid?.
• Pectin Unit Structure and Its Molecular structure.
• History and Discovery of MCP.
• Chemistry of MCP(Modified Citrus Pectin).
• Mechanism of Action and Research Updated.
• Clinical Indications of MCP(Modified Citrus Pectin).
• Reported Uses of MCP.
• Indications and Usage,Dosage and Administration.
• Modern Research of Modified citrus pectin (MCP).
• How MCP Works as a Gentle Chelator?.
• Research Update:Myrrh,Commiphora Myrrha.

What is Modified Citrus Pectin?:

Modified citrus pectin refers to citrus pectin which has been hydrolyzed to yield smaller molecular weight molecules which appears to render it more absorbable. Unmodified citrus pectin is not absorbable. Pectin (see Pectin) is a soluble fiber that is found in citrus fruits (oranges, lemons, grapefruits) and apples. Pectin obtained from orange or lemon rinds, both rich sources of pectin, is referred to as citrus pectin. Citrus pectin is a linear polysaccharide containing from about 300 to 1,000 monosaccharide units. D-galacturonic acid, an acid form of the sugar D-galactose, is the principal monosaccharide unit of citrus pectin. The D-galacturonic acid residues are bonded together by alpha-1,4 glycosidic linkages in linear chains. Neutral sugars, present in side chains on the pectin molecule, include D-galactose, L-arabinose, D-xylose and L-frucose. L-Rhamnose is also found in pectin. Some of the galacturonic acid residues in pectin are in the form of methyl esters. The molecular weight of citrus pectin ranges from 20,000 to 400,000 daltons, with the majority of the molecules having molecular weights ranging from 50,000 to 150,000 daltons.

 Modified citrus pectin is formed from citrus pectin via a depolymerization process in which citrus pectin is first treated with sodium hydroxide at a pH of 10 for a short time, and then hydrochloric acid at a pH of 3 for a much longer period of time. The pectin fragments that are formed are principally comprised of D-polygalacturonates, absent the methoxyl groups. The molecular weight of modified citrus pectin ranges from 1,000 to 15,000 daltons, with an average weight of about 10,000 daltons. Modified citrus pectin is comprised of linear polygalacturonate chains containing from 5 to 90 galacturonic acid residues, with an average of approximately 55 residues. Also present, are D-galactose residues in side chains. Modified citrus pectin is also known as modified pectin, depolymerized pectin and pH-modified pectin. It is abbreviated as MCP. It is water soluble.

Reference:

• 1.What is Modified Citrus Pectin,MCP,an inhibitor of cancer metastasis and its wide uses?

This article written and edited via herbalist of MDidea Extracts Professional. They run a range of online descriptions about this herb,including general information related and summarized updating discoveries from findings of professional scientisits this field related.Describe style aimed to form a useful detecting literature space where the intertwined threshold and related questions raise out and visualize themselves.

♣ last edit date:20th,Oct.2010.