Coptis Root,Golden Thread Root or Huang Lian:a Ranunculaceae family herb and its detoxification applications.
- Basic Information of Coptis Root
- Botanical Source of Coptis Root
- Character identification of the herb Coptis Root
- Preparation and Chemical Constituents of Coptis Root
- Nature Flavor,Channel Tropism and Indication of Coptis Root
- Administration and Dosage of Coptis Root
- Coptis Root and its Pharmacological Effects
Applications and Properties:
Indications:Hot and humid fullness,vomiting acid regurgitation,dysentery,jaundice,fever,coma,heat and hyperactivity,irritability,insomnia,palpitations,restlessness,hot spit blood nosebleed,red eyes,pain,diabetes,carbuncles sore treatment,foreign rule eczema,eczema,ear pus.
Purging fire,dry dampness,detoxification,insecticide.Treat seasonal toxic heat,typhoid fever,excessive heat upset,vomiting and fullness,dysentery,diarrhea,abdominal pain hot,according to pulmonary tuberculosis,spit,nosebleed,blood,diabetes,malnutrition, ascariasis,whooping cough,sore throat,fire eyes,mouth sores,sore ulcer,eczema,fire burns.
Treat Ulcer,Inhibition of Gastric Acid Secretion,Anti-inflammatory and analgesic,Antibacterial,Anti-pathogen,
Immunomodulatory and anti-inflammatory and antipyretic,Cardiovascular Effects,Regulation on blood lipids,blood glucose.
Clear heat and dry dampness,clear heat and drain fire,purging fire for removing toxin,dry dampness,detoxification.
The herb Rhizoma Coptidis(Coptis Root,Huang Lian) taste bitter nature cold.Enter into heart,spleen,stomach,liver,gallbladder,large intestine meridians.
In the TCM syste,the herb Rhizoma Coptidis(Coptis Root,Huang Lian) indicated for heat dampness distention and fullness,heat dampness and chest fullness,vomiting and acid regurgitation,diarrhoea(diarrhea,loose stools),dysentery,jaundice,hyperpyrexia and unconsciousness,hyperpyrexia due to pathogen in heart meridian,heart-fire hyperactivity(exuberance of heart fire),dysphoria,delirium or frenetic movement of hot blood caused blood vomiting,vexation and sleeplessness,blood-heat and vomiting blood,upset insomnia due to heart-fire hyperactivity,stomach heat and vomiting or rapid digestion of food and polyorexia,liver-fire and red eyes swelling pain,hot eyes(red eyes),toothache,consumptive thirst(drinking and urine,symptom-complex of excessive eating),abscess and hard furuncle,furunculosis and furuncle,pathopyretic ulcer,swelling and aching of gum,aphthous stomatitis(mouth and tongue sores),ting ear,genital swelling,hemorrhoids blood,eczema or wet sore,empyrosis(scald).external indicated for eczema,wet sore,ear pus.
Suggested Dosage internal as decoction 1.5~3grams,or grined as powder 0.3~0.6grams,or into pellets or powder.External proper amount,grined powder and apply,or decoct with water as a topical wash,or boil to paste,or juice.
Safety and Toxicity:
Cat oral 0.1g/kg can cause systemic suppression, vomiting, at 8 to 10 days after the death, breathing from excitement turned to paralysis, convulsions before death can occur. Mice injected with berberine sulfate LD50 is 24.3mg/kg. Tetrahydroberberine fed to mice, subcutaneous and intravenous lethal dose was 940mg/kg,790mg/kg and 100mg/kg.
Therapeutic dose of berberine quite safe, side effects are few long-term use has not been any obstacles, an oral or in conjunction berberine berberine berberine 2.0g powder 100g no any side effects. In animal studies,toxicity is also very light,easy lethal to mice orally, the minimum lethal dose intraperitoneal injection of 0.01g/kg, also measured obtaining the median lethal dose of 0.066g/kg (huang bo or huang lian each 0.52,0.73g/kg).
- 1.Coptis Root,Golden Thread Root or Huang Lian:a Ranunculaceae family herb and its detoxification applications.
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