Coptis Root, Golden Thread Root or Huang Lian: a Ranunculaceae family herb and its detoxification applications.
Applications and Properties:
Treat Ulcer,Inhibition of Gastric Acid Secretion,Anti-inflammatory and analgesic,Antibacterial,Anti-pathogen,
Immunomodulatory and anti-inflammatory and antipyretic,Cardiovascular Effects,Regulation on blood lipids,blood glucose.
Clear heat and dry dampness,clear heat and drain fire,purging fire for removing toxin,dry dampness,detoxification.
Modern herbalists found various useful properties of the herb Coptis Root(Huang Lian), some of them are known including:Inhibition of Gastric Acid Secretion, Treat Ulcer, Anti-inflammatory, and analgesic, Antibacterial, Anti-pathogen, Immunomodulatory, anti-inflammatory, antipyretic, Effects on digestive system, Cardiovascular Effect, Regulation on blood lipids, blood glucose, etc.
Common herbal classics noted the herb Coptis Root(Huang Lian) taste bitter and cold in nature.Enter into the heart, liver, stomach, large intestine meridians.
Safety and Toxicity:
Safety: The therapeutic dose of berberine quite safe, side effects are few long-term uses has not been any obstacles, an oral or in conjunction berberine berberine berberine 2.0g powder 100g no any side effects. In animal studies, toxicity is also very light, easy lethal to mice orally, the minimum lethal dose intraperitoneal injection of 0.01g/kg, also measured obtaining the median lethal dose of 0.066g/kg (Huang bo or Huang Lian each 0.52,0.73g/kg).
Toxicity: Cat oral 0.1g/kg can cause systemic suppression, vomiting, at 8 to 10 days after the death, breathing from excitement turned to paralysis, convulsions before death can occur. Mice injected with berberine sulfate LD50 is 24.3mg/kg. Tetrahydroberberine fed to mice, subcutaneous and intravenous lethal dose was 940mg/kg,790mg/kg and 100mg/kg.
- 1.Coptis Root, Golden Thread Root or Huang Lian: a Ranunculaceae family herb and its detoxification applications.
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